<div class="cit"><a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed/25711174">http://www.ncbi.nlm.nih.gov/pubmed/25711174</a></div> <div class="cit" style="font-size:.8465em;line-height:1.45em;font-family:arial, helvetica, clean, sans-serif;"><br></div> <div class="cit" style="font-size:.8465em;line-height:1.45em;font-family:arial, helvetica, clean, sans-serif;"><span><a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed/25711174#" title="The journal of sexual medicine." style="color:#660066;border-bottom-width:0px;" target="_blank">J Sex Med.</a></span> 2015 Apr;12(4):1004-11. doi: 10.1111/jsm.12847. Epub 2015 Feb 25.</div> <h1 style="font-size:1.231em;margin:.375em 0px;line-height:1.125em;font-family:arial, helvetica, clean, sans-serif;">Common genetic factors among <span class="highlight">sexual orientation</span>, gender nonconformity, and number of sex partners in female twins: implications for the evolution of homosexuality.</h1> <div><br></div> <div> <h4 style="font-size:13px;margin:0px .25em 0px 0px;text-transform:uppercase;float:left;font-family:arial, helvetica, clean, sans-serif;line-height:17.9998016357422px;">CONCLUSIONS:</h4> <p style="margin:0px 0px .5em;font-family:arial, helvetica, clean, sans-serif;font-size:13px;line-height:17.9998016357422px;">Our findings suggest that genetic factors responsible for nonheterosexuality are shared with genetic factors responsible for the number of lifetime <span class="highlight">sexual</span> partners via a latent sex typicality phenotype in human females. These results may have implications for evolutionary models of homosexuality but are limited by potential mediating variables (such as personality traits) and measurement issues.</p> <p style="margin:0px 0px .5em;font-family:arial, helvetica, clean, sans-serif;font-size:13px;line-height:17.9998016357422px;"><br></p> <p style="margin:0px 0px .5em;"><font face="arial, helvetica, clean, sans-serif"><a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed/25399360">http://www.ncbi.nlm.nih.gov/pubmed/25399360</a></font></p> <p style="margin:0px 0px .5em;"><font face="arial, helvetica, clean, sans-serif"><br></font></p> <div class="cit" style="font-size:.8465em;line-height:1.45em;font-family:arial, helvetica, clean, sans-serif;"><span><a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed/25399360#" title="Psychological medicine." style="color:#660066;border-bottom-width:0px;" target="_blank">Psychol Med.</a></span> 2015 May;45(7):1379-88. doi: 10.1017/S0033291714002451. Epub 2014 Nov 17.</div> <p style="margin:0px 0px .5em;"></p> <h1 style="font-size:1.231em;margin:.375em 0px;line-height:1.125em;font-family:arial, helvetica, clean, sans-serif;">Genome-wide scan demonstrates significant linkage for male <span class="highlight">sexual orientation</span>.</h1></div> <div><br></div> <div> <h4 style="font-size:13px;margin:0px .25em 0px 0px;text-transform:uppercase;float:left;font-family:arial, helvetica, clean, sans-serif;line-height:17.9998016357422px;">CONCLUSIONS:</h4> <p style="margin:0px 0px .5em;font-family:arial, helvetica, clean, sans-serif;font-size:13px;line-height:17.9998016357422px;">Results, especially in the context of past studies, support the existence of genes on pericentromeric chromosome 8 and chromosome Xq28 influencing development of male <span class="highlight">sexual orientation</span>.</p> <p style="margin:0px 0px .5em;font-family:arial, helvetica, clean, sans-serif;font-size:13px;line-height:17.9998016357422px;"><br></p> <p style="margin:0px 0px .5em;font-family:arial, helvetica, clean, sans-serif;font-size:13px;line-height:17.9998016357422px;"><span style="line-height:17.9998016357422px;"><a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed/25172350">http://www.ncbi.nlm.nih.gov/pubmed/25172350</a></span></p> <p style="margin:0px 0px .5em;font-family:arial, helvetica, clean, sans-serif;font-size:13px;line-height:17.9998016357422px;"><span style="line-height:17.9998016357422px;"><br></span></p> <div class="cit" style="font-size:.8465em;line-height:1.45em;font-family:arial, helvetica, clean, sans-serif;"><span><a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed/25172350#" title="Advances in genetics." style="color:#660066;border-bottom-width:0px;" target="_blank">Adv Genet.</a></span> 2014;86:167-84. doi: 10.1016/B978-0-12-800222-3.00008-5.</div> <h1 style="font-size:1.231em;margin:.375em 0px;line-height:1.125em;font-family:arial, helvetica, clean, sans-serif;">The biological basis of human <span class="highlight">sexual orientation</span>: is there a role for epigenetics?</h1></div> <div><br></div> <div> <h3 style="font-size:1.0769em;line-height:1.2857;margin:0px;color:#985735;display:inline;font-family:arial, helvetica, clean, sans-serif;">Abstract</h3> <div style="font-family:arial, helvetica, clean, sans-serif;font-size:13px;line-height:17.9998016357422px;"> <p style="margin:0px 0px .5em;"><span class="highlight">Sexual orientation</span> is one of the largest sex differences in humans. The vast majority of the population is heterosexual, that is, they are attracted to members of the opposite sex. However, a small but significant proportion of people are bisexual or homosexual and experience attraction to members of the same sex. The origins of the phenomenon have long been the subject of scientific study. In this chapter, we will review the evidence that <span class="highlight">sexual orientation</span> has biological underpinnings and consider the involvement of epigenetic mechanisms. We will first discuss studies that show that <span class="highlight">sexual orientation</span> has a genetic component. These studies show that <span class="highlight">sexual orientation</span> is more concordant in monozygotic twins than in dizygotic ones and that male <span class="highlight">sexual orientation</span> is linked to several regions of the genome. We will then highlight findings that suggest a link between<span class="highlight">sexual orientation</span> and epigenetic mechanisms. In particular, we will consider the case of women with congenital adrenal hyperplasia (CAH). These women were exposed to high levels of testosterone in utero and have much higher rates of nonheterosexual <span class="highlight">orientation</span> compared to non-CAH women. Studies in animal models strongly suggest that the long-term effects of hormonal exposure (such as those experienced by CAH women) are mediated by epigenetic mechanisms. We conclude by describing a hypothetical framework that unifies genetic and epigenetic explanations of <span class="highlight">sexual orientation</span> and the continued challenges facing <span class="highlight">sexual orientation</span> research.</p> <p style="margin:0px 0px .5em;"><br></p> <p style="margin:0px 0px .5em;"><br></p> <p style="margin:0px 0px .5em;">성적 지향성(이성애, 동성애, 양성애)이 유전자와 연관되어있다는 점은 이미 학계에선 기본 전제로 깔고 있습니다.</p> <p style="margin:0px 0px .5em;">근래의 연구들은 과연 '어떤' 유전자가 관여하는지, 호르몬 등의 요소와 연관성은 없는지 등을 확인하고 있죠.</p> <p style="margin:0px 0px .5em;">기사를 통해 '아냐 동성애는 후천적이야!'라고 주장하셔도 그 정도 근거수준으론 의미가 없습니다.</p></div></div>