<font size="3"> </font> <div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0"><span style='line-height: 130%; font-family: "바탕","serif"; mso-bidi-font-size: 10.0pt'><font size="2">본 실험은 종양 치료에서 사용되는 약물이 체내의 특성에 따라 어떻게 방출이 되는지 확인하기 위해 시행하였다<span lang="EN-US">. </span>파클리탁셀은 종양을 치료하기 위한 요법 중 하나로 가장 광범위하고 효과적인 화학 약물이다<span lang="EN-US">. </span>파클리탁셀의<span lang="EN-US"> Disk </span>제작 과정에서 다량의 고가 약물이 소비 되므로 같은 소수성 성질을 지닌<span lang="EN-US"> acetaminophen</span>을<span lang="EN-US"> model drug</span>로 사용하였다<span lang="EN-US">. </span>그리고 속도 제어를 위하여<span lang="EN-US">PEVA</span>로 코팅하여 실험하였다<span lang="EN-US">. </span>체내 이식용 임플란트에서의 표면에서 약물을 방출하는 특성은 인체온도인<span lang="EN-US"> 37</span>℃를 기준으로 평가하고 있으며 많은 연구 결과들이 보고되어지고 있다<span lang="EN-US">. </span>그러나 특정한 온도조건에서 종양 치료를 실시하는 능동형 약물방출특성에 관한 연구보고는 아직 이루어지지 않고 있다<span lang="EN-US">. </span>특정한 온도 조건에서 적절한 양의 약물을 방출하기 위해서는 약물을 포함하는 코팅층의 제작에 관한 연구가 필요하며 특정온도에서 약물방출특성에 관한 연구가 필수적이다<span lang="EN-US">. </span>시험은 시간<span lang="EN-US">, </span>배율 그리고 온도조건에 따라서 약물 방출 정도를 분석하였다<span lang="EN-US">.</span></font></span></div> <div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0"><span style='line-height: 130%; font-family: "바탕","serif"; mso-bidi-font-size: 10.0pt'><font size="2"><span lang="EN-US"></span></font></span> </div> <div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0"> </div><span style='line-height: 130%; font-family: "바탕","serif"; mso-bidi-font-size: 10.0pt'><font size="2"><span lang="EN-US"><o:p><div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0"><span class="hps"><span lang="EN" style='color: rgb(51, 51, 51); font-family: "Arial","sans-serif"; mso-ansi-language: EN'>This</span></span><span lang="EN" style='color: rgb(51, 51, 51); font-family: "Arial","sans-serif"; mso-ansi-language: EN'> <span class="hps">experiment was</span> <span class="hps">conducted to</span> <span class="hps">confirm that</span> <span class="hps">how</span> <span class="hps">there is a</span> <span class="hps">release drug</span> <span class="hps">used in the treatment of</span> <span class="hps">tumors</span> <span class="hps">according to the characteristics of</span> <span class="hps">the body</span>. <span class="hps">Paclitaxel</span><span class="hps">is</span> <span class="hps">chemical</span> <span class="hps">agents</span><span class="hps">and effective</span> <span class="hps">broadest</span> <span class="hps">either</span> <span class="hps">treatments</span> <span class="hps">for treating</span> <span class="hps">tumors.</span> <span class="hps">I</span> <span class="hps">was used as</span> <span class="hps">a</span> <span class="hps">model drug</span> <span class="hps">acetaminophen</span> <span class="hps">with a</span> <span class="hps">hydrophobic nature</span>, such as <span class="hps">for</span> <span class="hps">an expensive</span> <span class="hps">large amount of</span> <span class="hps">drug</span> <span class="hps">is used in the</span> <span class="hps">production process</span> <span class="hps">of</span> <span class="hps">Disk</span> <span class="hps">paclitaxel</span>. <span class="hps">Then,</span> <span class="hps">the experiment was carried out</span> <span class="hps">by coating</span> <span class="hps">with</span> <span class="hps">PEVA</span> <span class="hps">for speed</span><span class="hps">control</span>. <span class="hps">It has</span> <span class="hps">been</span><span class="hps">evaluated</span> <span class="hps">based on the</span> <span class="hps">37 </span></span><span class="hps"><span style="color: rgb(51, 51, 51); font-family: 굴림; mso-bidi-font-family: 굴림; mso-ansi-language: EN">℃</span></span><span style='color: rgb(51, 51, 51); font-family: "Arial","sans-serif"; mso-ansi-language: EN'> <span class="hps"><span lang="EN">is the temperature of the</span></span><span lang="EN"> <span class="hps">human body</span>, <span class="hps">characteristics</span> <span class="hps">release the drug</span> <span class="hps">on the surface of the</span> <span class="hps">graft</span> <span class="hps">implant</span> <span class="hps">has</span><span class="hps">been</span> <span class="hps">reported</span> <span class="hps">many research results</span>. <span class="hps">However, the</span> <span class="hps">specific temperature conditions</span>, <span class="hps">report</span> <span class="hps">on</span><span class="hps">active</span> <span class="hps">drug release</span> <span class="hps">characteristics</span> <span class="hps">for performing</span> <span class="hps">the</span> <span class="hps">treatment of</span> <span class="hps">tumors</span><span class="hps">have not</span> <span class="hps">been made</span> <span class="hps">yet</span>. <span class="hps">To</span> <span class="hps">at</span> <span class="hps">specific temperature conditions</span> <span class="hps">and to</span> <span class="hps">release the drug</span> <span class="hps">appropriate amount of</span> <span class="hps">research</span> <span class="hps">on the preparation</span> <span class="hps">of a coating</span> <span class="hps">layer containing</span> <span class="hps">a</span> <span class="hps">drug</span> <span class="hps">is necessary</span>, <span class="hps">research on</span> <span class="hps">drug release</span> <span class="hps">characteristics</span> <span class="hps">at a particular temperature</span><span class="hps">is essential</span>. <span class="hps">Time</span>, <span class="hps">tests were</span> <span class="hps">analyzed</span> <span class="hps">the extent of</span> <span class="hps">drug release</span> <span class="hps">by</span> <span class="hps">temperature conditions</span> <span class="hps">and</span> <span class="hps">magnifications</span>.</span></span><b style="mso-bidi-font-weight: normal"><span lang="EN-US" style='line-height: 130%; font-family: "바탕","serif"; mso-bidi-font-size: 10.0pt'><o:p></o:p></span></b></div> <div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0"><font face="굴림" size="3"> </font></div></o:p> <div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0"> </div></span> <div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0">이렇게 했는데 이게 맞나요 ?;;</div> <div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0">영어를 보면 대충 해석은 되는데 이제 정확한 문장이 되는지 </div> <div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0">짧은 영어 실력으로 맞는지 잘 모르겠네요 </div></font> <div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0"> </div></span> <div class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 130%; text-indent: 10pt; mso-char-indent-count: 1.0"> </div><font size="3"> </font>